Have you ever mastered any sort of game/sport to the point where it stops being fun? That's what Big XII football was getting to be like in Norman (seriously, no one wins 6 straight conference titles in any decent league).
OU is definitely going to lose a lot more games in the SEC, and there certainly won't be any "sexpeat" of conference titles, but OU will also play in and win a lot more regular-season big games, which were far too few in the Big XII.
BTW, Dan-O, is that your turkey leg from 2013?